I went from Studio One 4 to Cubase 10 (now 11) Pro and for Orchestral I'm totally happy. I will say that Studio One 5.2 has come of age for the most part. So I run that on my laptop for my own fun and sketching and mobile tracking, and keep Cubase on my tower. Cubase is so vast and has so much from 30 years of development, it's truly a one-stop shopping, but you have to be Ok with that much STUFF in a DAW. As a software developer for over 20 years I'm totally fine with all the hidden caves in Cubase.
The latest and greatest feature in Cubase as a mix engineer is Control Room. Where has this been al my life! I can put SonarWorks in there and never ever make a boo boo and send a client something where I forgot to remove it. Easy peazy A/B checking, switch to mono and it can be automated. LOVE IT. And if someone else is mastering the project, I can put all mixbuss effects in Control Room so I hear the effect but it stays clear of the output so the mastering engineer gets just the mix. Doesn't sound like a dealbreaker, but wait until you send your first paid project to a client and forget to remove the mixbuss plugins that shouldn't be there, and it sounds horrid on their end.
I ran Studio one 3 and 4 for several years, now I've used Cubase for 2 years and I'm totally committed to Cubase pro as my DAW. Check that box off, other mountains to climb! OH, the reason: I run Windows, not a Mac. I still believe that Cubase and Studio One are great choices for the Windows platform. If I were doing rock/pop/EDM, I'd be Studio One all the way. For MIDI Orchestration, Cubase. The support for Cubase all over YouTube University is nuts, you almost never need to pay for training. Ba Da Bing.